%0 Journal Article
%T A Genome-Wide Detection of Copy Number Variations Using SNP Genotyping Arrays in Braque Fran£¿ais Type Pyr¨¦n¨¦es Dogs
%A Andrea Spaterna
%A Baldassare Portolano
%A Filippo Biscarini
%A Marco Ragatzu
%A Maria Teresa Sardina
%A Roberta Ciampolini
%A Salvatore Mastrangelo
%J Archive of "Animals : an Open Access Journal from MDPI".
%D 2019
%R 10.3390/ani9030077
%X Copy number variations (CNVs) are important sources of variation in mammalian species. In this study, we used a single nucleotide polymorphisms (SNP) array to detect CNVs in Braque Fran£¿ais, type Pyr¨¦n¨¦es dogs (BRA). Results overlapped moderately in comparison with previous studies on CNVs in dogs, leading to the identification of 16 novel CNVRs. Several genes were annotated in the CNV regions (CNVRs) detected, some of which related to muscle structure development. This breed is known to be excellent upland game birds dogs. The selection for such hunting behavior could have driven the presence of these genes into the CNVRs. Copy number variations may be of interest to study associations between genomic and phenotypic variation
%K copy number variation (CNV)
%K canine high-density SNP array
%K Braque Fran£¿ais type Pyr¨¦n¨¦es dogs
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466271/