%0 Journal Article %T Anesthetic Considerations for Patients on Antidepressant Therapy ¨C Part II %A Elliot V. Hersh %A Leonard Golden %A Mana Saraghi %J Archive of "Anesthesia Progress". %D 2018 %R 10.2344/anpr-65-01-10 %X Millions of patients take antidepressant medications in the United States for the treatment of depression or anxiety disorders. Some antidepressants are prescribed off-label to treat problems such as chronic pain, low energy, and menstrual symptoms. Antidepressants are a broad and expansive group of medications, but the more common drug classes include tricyclic antidepressants, selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake inhibitors, and monoamine oxidase inhibitors. A miscellaneous or ¡°atypical¡± category covers other agents. Some herbal supplements that claim to have antidepressant activity will also be discussed. Part I of this series reviewed antidepressant pharmacology, adverse effects, and drug interactions with adrenergic agonists. In part II, drug¨Cdrug interactions with sedation and general anesthetics, bleeding effects, and serotonin syndrome will be discussed %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841487/