%0 Journal Article %T Teriflunomide induces a tolerogenic bias in blood immune cells of MS patients %A Amalia Tejeda©\Velarde %A Enric Monreal %A Ernesto Rold¨¢n %A Eulalia Rodr¨ªguez©\Mart¨ªn %A Jos¨¦ C. ¨¢lvarez©\Cerme£¿o %A Lucienne Costa©\Frossard %A Noelia Villarrubia %A Rafael Arroyo %A Roberto ¨¢lvarez©\Lafuente %A Silvia Medina %A Susana Sainz de la Maza %J Archive of "Annals of Clinical and Translational Neurology". %D 2019 %R 10.1002/acn3.711 %X Teriflunomide, a disease©\modifying treatment approved for multiple sclerosis (MS), inhibits reversibly dihydroorotate dehydrogenase, an enzyme involved in de novo pyrimidine biosynthesis and down©\regulates proliferation of activated lymphocytes. We aimed to study the impact of this drug in the lymphocyte profiles of MS patients %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389853/