%0 Journal Article %T A Cost Effective (QbD) Approach in the Development and Optimization of Rosiglitazone Maleate Mucoadhesive Extended Release Tablets ¨CIn Vitro and Ex Vivo %A Eranti Bhargav %A Haranath Chinthaginjala %A Mallela Vijaya Jyothi %A Moinuddin Syed %A Mounika Jutur %A Mrunalini Poura %A Mujahid Shaik Mahammad %A Muralidhar Pisay %A Sailaja Yadav %A Suryaprakash Reddy Chappidi %A Venkataranganna Marikunte %J Archive of "Advanced Pharmaceutical Bulletin". %D 2019 %R 10.15171/apb.2019.032 %X Purpose: The purpose of the study was to develop and optimize rosiglitazone maleate mucoadhesive extended-release tablets by quality by design (QbD) approach. Based on QTPP (quality target product profile) CQAs (critical quality attributes) were identified %K Quality by design %K Design of experiment %K Carbopol 934P %K Sodium carboxymethyl cellulose %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664114/