%0 Journal Article %T Using Ketamine and Propofol for Procedural Sedation of Adults in the Emergency Department: A Systematic Review and Meta-Analysis %A Hassan Soleimanpour %A Morteza Ghojazadeh %A Sahba-Sadat Faghih %A Sarvin Sanaie %A Seyed Pouya Paknezhad %J Archive of "Advanced Pharmaceutical Bulletin". %D 2019 %R 10.15171/apb.2019.002 %X Purpose: Ketamine-propofol combination (ketofol) is being used to provide a safe and effective procedural sedation (PS) in emergency department (ED) and may theoretically have beneficial effects since using lower doses of each drug may result in a reduction of the adverse events of both agents while maintaining optimal conditions for performing procedures. This systematic review was conducted to evaluate the efficacy, advantages and disadvantages of these two drugs for PS %K Ketamine %K Propofol %K Procedural sedation %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468222/