%0 Journal Article %T Factors affecting the harmonization of disease-related metabolic brain pattern expression quantification in [18F]FDG-PET (PETMETPAT) %A Bas A. de Jong %A Daniela Perani %A JPND-PETMETPAT Working Group %A Klaus L. Leenders %A Paul J.H. van Snick %A Remco J. Renken %A Ronald Boellaard %A Sandeep Golla %A Sanne K. Meles %A Sjoerd Rijnsdorp %J Archive of "Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring". %D 2019 %R 10.1016/j.dadm.2019.04.002 %X The implementation of spatial-covariance [18F]fluorodeoxyglucose positron emission tomography¨Cbased disease-related metabolic brain patterns as biomarkers has been hampered by intercenter imaging differences. Within the scope of the JPND-PETMETPAT working group, we illustrate the impact of these differences on Parkinson's disease¨Crelated pattern (PDRP) expression scores %K Neuroimaging biomarker %K FDG-PET %K Harmonization %K Hoffman 3D brain phantom %K Principal component analysis %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595051/