%0 Journal Article
%T Evaluation of rs1957106 Polymorphism of NF-百BI in Glioblastoma Multiforme in Isfahan, Iran
%A Laleh Rafiee
%A Mohamadhasan Tajadini
%A Pouya Tabatabaei Irani
%A Shaghayegh Haghjooy Javanmard
%A Yasaman Sadeghi
%J Archive of "Advanced Biomedical Research".
%D 2019
%R 10.4103/abr.abr_227_18
%X The kB family of nuclear factor (NF-百B) is a series of transcription factors that plays a key role in regulation of immunity, cell growth, and apoptosis and is considered as the main downstream component of epidermal growth factor receptor for which there are evidence of excessive activity in most cases of glioblastoma multiform (GBM). Thus, the current information has gained evidence on NF-百BIA tumor suppressor role in GMB. SNP rs1957106 was diagnosed as a new polymorphism which affected the expression of NF-百BI and causes activation of NF-百B in GBM patients
%K Glioblastoma
%K NF-百BI
%K polymorphism
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385670/