%0 Journal Article
%T Intergenotypic 2k/1b hepatitis C virus recombinants in the East Macedonia and Thrace region of Greece
%A Eleni Kokkiou
%A Fani Souvalidou
%A Ioannis Karakasiliotis
%A John Koskinas
%A Katerina Kassela
%A Konstantinos Mimidis
%A Maria Panopoulou
%A Panayotis Mimidis
%A Penelope Mavromara
%A Stavroula Veletza
%J Archive of "Annals of Gastroenterology".
%D 2019
%R 10.20524/aog.2018.0322
%X Intergenotypic recombinant hepatitis C virus (HCV) strains emerge rarely during coinfection of the same individual with two HCV genotypes. Few recombinant HCV strains have been identified to date and only one, CRF01 2k/1b, has become a worldwide concern. This study reevaluated the genotyping of three HCV genotype 2 strains from a group of patients with an unusually low rate of sustained virological response after pegylated interferon/ribavirin treatment. In addition, genetic determinants of host interferon resistance were evaluated
%K Hepatitis C virus
%K IFN-resistance
%K phylogenetic analysis
%K recombination
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302191/