%0 Journal Article %T Sample Size Calculation Guide - Part 3: How to Calculate the Sample Size for an Independent Case-control Study %A Ahmed Khaled Fahim %A Ahmed Negida %A Nadien Khaled Fahim %J Archive of "Advanced Journal of Emergency Medicine". %D 2019 %R 10.22114/AJEM.v0i0.138 %X In the previous educational articles, we explained how to calculate the sample size for a rate or a single proportion and how to calculate the sample size for an independent cohort study (1, 2). In this article, we will explain how to calculate the sample size for an independent case-control study based on the odds ratios or two proportions representing the exposure rates in the case and the control groups %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548115/