%0 Journal Article %T Germ Cell Tumors: Updates on Epidemiology, Biology, and Treatment Considerations %A Aditya Bagrodia %A Costantine Albany %A Timothy A. Masterson %J Archive of "Advances in Urology". %D 2018 %R 10.1155/2018/4821084 %X Germ cell tumors (GCTs) are the most common solid tumors in young men. GCTs represent a rare oncologic success story with 5-year cure rates exceeding 98% for early-stage tumors and 80% for patients with metastatic disease, attributable to the integration of surgery, cisplatin-based chemotherapy, and radiation therapy. Despite the excellent clinical outcomes in testicular GCTs, significant challenges and opportunities exist, as GCTs represent the most life years lost for nonpediatric malignancies [1] %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120297/