%0 Journal Article %T 2018 Year in Review in Critical Care %A Alaa Gouda %A Yaseen M. Arabi %A Youssuf A. Ali %J Archive of "Annals of Thoracic Medicine". %D 2019 %R 10.4103/atm.ATM_72_19 %X The objective of this review is to highlight major randomized controlled trials (RCTs) in critical care in 2018. Through literature search, we identified 16 studies published in the year 2018 in high impact medical journals. These studies have been chosen based on the significance and the relevance of questions addressed and on the methodology. Common features among these studies include the large number of patients, being multicenter and multinational and the generalizability of the results to multiple and heterogeneous settings. The articles were grouped based on major area of focus and the clinical question that has been investigated %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467021/