%0 Journal Article %T Effect of transoral tracheal wash on respiratory mechanics in dogs with respiratory disease %A Armelle M. deLaforcade %A Elizabeth A. Rozanski %A Meghan E. Vaught %J Archive of "Canadian Journal of Veterinary Research". %D 2018 %X The purpose of this study was to determine the impact of a transoral tracheal wash (TOTW) on respiratory mechanics in dogs and to describe the use of a critical care ventilator (CCV) to determine respiratory mechanics. Fourteen client-owned dogs with respiratory diseases were enrolled. Respiratory mechanics, including static compliance (Cstat) and static resistance (Rstat), were determined before and after TOTW. Pre- and post-wash results were compared, with a P-value of < 0.05 considered significant. The mean ¡À standard deviation (SD) value of Cstat pre-TOTW was 1.59 ¡À 0.94 mL/cmH2O/kg while the mean ¡À SD of Cstat post-TOTW was 1.29 ¡À 0.71 mL/cmH2O/kg (P = 0.045). The median Rstat was not significantly different pre- and post-wash. The transoral tracheal wash altered respiratory mechanics, as observed by a reduction in Cstat, presumably due to airway flooding and collapse. While no long-lasting effects were noted in these clinical patients, this effect should be considered when performing TOTW on dogs with respiratory diseases. Respiratory mechanics testing using a CCV was feasible and may be a useful clinical testing approach %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764042/