%0 Journal Article
%T The ionophore antibiotic gramicidin A inhibits pancreatic cancer stem cells associated with CD47 down-regulation
%A Jing Geng
%A Min Jiang
%A Rui-Qi Wang
%A Wei-Jin Sheng
%A Xiu-Jun Liu
%A Yong-Su Zhen
%J Archive of "Cancer Cell International".
%D 2019
%R 10.1186/s12935-019-0862-6
%X Tumorsphere formation assay. a Representative images of tumor spheres in BxPC-3 and MIA PaCa-2 cells obtained before treatment (scale bar: 100 ¦Ìm). b Representative images of BxPC-3 and MIA PaCa-2 tumorspheres obtained after the treatment with the indicated concentrations of GrA for 7 days (scale bar: 50 ¦Ìm). c Statistical analysis of the number (% of control) of BxPC-3 and MIA PaCa-2 tumorspheres treated with GrA or Sal for 7 days, tumorsphere numbers were presented as mean£¿¡À£¿SD from 3 replicated wells. *P£¿<£¿0.05, **P£¿<£¿0.01, #P£¿<£¿0.05 vs contro
%K Gramicidin A
%K Ionophore antibiotic
%K Cancer stem cell
%K CD47
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532126/