%0 Journal Article
%T Cervical cancer screening history prior to a diagnosis of cervical cancer in Danish women aged 60£¿years and older¡ªA national cohort study
%A Anne Hammer
%A Jan Blaakaer
%A Rikke D. Maimburg
%A Vibeke Soegaard
%J Archive of "Cancer Medicine".
%D 2019
%R 10.1002/cam4.1926
%X The incidence and mortality of cervical cancer are high in Danish women aged 60 years and older who are about to exit the cervical cancer screening program. The present study aimed to describe the screening history in women ¡Ý60 years old, diagnosed with cervical cancer in Denmark, 2009©\2013. We retrieved information on cases of cervical cancer and previous cervical cancer screening from national registries. During the study period, a total of 1907 women were diagnosed with cervical cancer, 574 (30.1%) of which were ¡Ý60 years old. The majority of women were diagnosed with squamous cell carcinoma (73.7%) and advanced©\stage disease (ASD, ie, ¡ÝFIGO IIB; 63.1%). The proportion of ASD increased with age, from 51.9% in women aged 60©\64% to 76.7% in women aged 75©\79. Among screened women (n = 377), 22.8% had a cervical cytology within 5 years of diagnosis, 73.3% of which were normal, and 45.1% were diagnosed with ASD. Women who had been sufficiently screened prior to screening exit (¡Ý2 normal cytology test in the age interval 50©\59) accounted for 18.1%. Of note, 53.8% of the sufficiently screened women were diagnosed with ASD. Sufficiently screened women were less likely to be diagnosed with ASD compared to never©\screened women (53.8% vs 67.5%, P < 0.020), but no difference was observed between sufficiently and insufficiently screened women (53.8% vs 63.4%, P = 0.091). Our findings suggest that cancer in older women may occur due to insufficient screening prior to screening exit, a low sensitivity of screening, and premature screening exit
%K cancer prevention
%K epidemiology and prevention
%K gynecological oncology
%K screening
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346234/