%0 Journal Article %T The prognostic impact of programmed cell death 1 and its ligand and the correlation with epithelial©\mesenchymal transition in thymic carcinoma %A Eiichi Mori %A Eriko Fukui %A Masato Minami %A Meinoshin Okumura %A Naoko Ose %A Ryu Kanzaki %A Soichiro Funaki %A Takashi Kanou %A Yasushi Shintani %A Yoko Yamamoto %J Archive of "Cancer Medicine". %D 2019 %R 10.1002/cam4.1943 %X The significance of epithelial©\mesenchymal transition (EMT) and immune checkpoint proteins in thymic carcinoma remains unknown. We examined the clinical significance of EMT, tumor©\infiltrating lymphocytes expressing the immune checkpoint protein, programmed cell death 1 (PD©\1 + TILs), and the expression of PD©\1 ligand 1 (PD©\L1) in thymic carcinoma (TC). We also investigated the relationships between these immune checkpoint proteins and the EMT status and examined the impact of induction chemotherapy on patients with tumors that express these proteins %K epithelial©\mesenchymal transition %K induction therapy %K PD©\1/PD©\L1 %K TGF©\¦Â %K thymic carcinoma %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346217/