%0 Journal Article
%T Outcomes Following Macrolide Use in Kidney Transplant Recipients
%A Amit X. Garg
%A Anita Lloyd
%A Anita Wong-Chan
%A Branko Braam
%A Brenda Hemmelgarn
%A Kevin Wen
%A Krista L. Lentine
%A Ngan N. Lam
%A Pietro Ravani
%A Rachel Jeong
%A Robert R. Quinn
%A Sita Gourishankar
%J Archive of "Canadian Journal of Kidney Health and Disease".
%D 2019
%R 10.1177/2054358119830706
%X Calcineurin inhibitors (CNI; cyclosporine, tacrolimus) are critical for kidney transplant immunosuppression, but have multiple potential drug interactions, such as with macrolide antibiotics. Macrolide antibiotics (clarithromycin, erythromycin, and azithromycin) are often used to treat atypical infections. Clarithromycin and erythromycin inhibit CNI metabolism and increase the risk of CNI nephrotoxicity, while azithromycin does not
%K adverse drug event
%K macrolide
%K calcineurin inhibitor
%K kidney transplant
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385328/