%0 Journal Article %T Therapeutic Effects of Prolonged Cannabidiol Treatment on Psychological Symptoms and Cognitive Function in Regular Cannabis Users: A Pragmatic Open-Label Clinical Trial %A Camilla Beale %A Chao Suo %A Hendrika van Hell %A Jennifer H. Martin %A Julie-Anne Prick %A Lisa-marie Greenwood %A Murat Y¨ącel %A Nadia Solowij %A Nagesh Pai %A Peter Galettis %A Rodney J. Croft %A Samantha J. Broyd %A Shanlin Fu %J Archive of "Cannabis and Cannabinoid Research". %D 2018 %R 10.1089/can.2017.0043 %X Introduction: Chronic cannabis use has been associated with impaired cognition and elevated psychological symptoms, particularly psychotic-like experiences. While ¦¤9-tetrahydrocannabinol (THC) is thought to be primarily responsible for these deleterious effects, cannabidiol (CBD) is purported to have antipsychotic properties and to ameliorate cognitive, symptomatic, and brain harms in cannabis users. However, this has never been tested in a prolonged administration trial in otherwise healthy cannabis users. Here, we report the first study of prolonged CBD administration to a community sample of regular cannabis users in a pragmatic trial investigating potential restorative effects of CBD on psychological symptoms and cognition %K cannabidiol %K cannabis %K attention %K memory %K psychological symptoms %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870061/