%0 Journal Article
%T Impaired dendritic cell functions in lung cancer: a review of recent advances and future perspectives
%A Fu-Rong Li
%A Jing-Bo Wang
%A Xue Huang
%J Archive of "Cancer Communications".
%D 2019
%R 10.1186/s40880-019-0387-3
%X Origin of DCs. MDPs among hematopoietic stem cells give rise to common FLT3-expressing CMPs, which are the precursors of pre-cDCs and pDCs. Monocytes can differentiate into MODCs under the appropriate circumstances and Pre-cDCs circulate into lung tissue and differentiate into different classes of DCs. MDP: Monocyte-DC progenitors; FLT3: colony stimulating factor 1 receptor (FMS)-like tyrosine kinase 3; pDC: plasmacytoid DC; cDC: conventional DC; MODCs: monocyte-derived DCs: CMPs: common myeloid progenitor
%K Lung cancer
%K Dendritic cell
%K Immune regulation
%K Immunotherapy
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631514/