%0 Journal Article %T Biomarker driven treatment of head and neck squamous cell cancer %A Barbara Burtness %A Nnamdi Eze %A Ying-Chun Lo %J Archive of "Cancers of the Head & Neck". %D 2017 %R 10.1186/s41199-017-0025-1 %X EGFR and receptor tyrosine kinase signaling in head and neck cancer. Resistance to EGFR inhibition may arise via signaling from redundant tyrosine kinases, such as HER family members, as well as downstream signaling activation. These may be important biomarkers predicting therapeutic response in head and neck cance %K Head and neck squamous cell cancer (HNSCC) %K Biomarkers %K Human papilloma virus (HPV) %K Epidermal growth factor receptor (EGFR) %K Epstein Barr virus (EBV) %K Cetuximab %K Nasopharyngeal carcinoma (NPC) %K Phosphatase and tensin homolog (PTEN) %K Phosphoinositide 3- kinase (PI3K) %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460531/