%0 Journal Article %T Combined ¦Á-programmed death-1 monoclonal antibody blockade and fractionated radiation therapy reduces tumor growth in mouse EL4 lymphoma %A Bevan Yueh %A Haichun Lai %A Huanjiao Weng %A Huichun Gong %A Jianbo Yang %A Jiani Xiong %A Jinxiang Lin %A Jizhen Lin %A Luke Morton %A Niangmei Cheng %A Pan Jiang %A Qianqian Xu %A Qiong Zhang %A Rong Jin %A Shubin Fang %A Shuchun Lin %A Tao Zeng %A Xinling Tian %A Xiufeng Li %A Xiuyun Lin %A Yunlu Xu %A Zhiwei Chen %J Archive of "Cancer Biology & Therapy". %D 2019 %R 10.1080/15384047.2018.1550569 %X The programmed death (PD) pathway is frequently present in the tumor microenvironment (TME) and suppresses tumor immunity by inhibiting the activity of tumor-infiltrating lymphocytes (TILs), particularly, CD8+ lymphocytes. PD immunotherapy involves stimulation of the immune response in the region surrounding the tumor but is insufficient to prevent tumor progression. Therefore, in this study, we examined the effects of combined PD immunotherapy with fractionated radiotherapy (RT) on antitumor immunity and tumor growth in lymphoma %K fractionated radiotherapy %K programmed death-1 %K programmed death ligand-1 %K antitumor immunity %K scheme %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605991/