%0 Journal Article %T Endocannabinoid-Enhanced ˇ°Likingˇ± in Nucleus Accumbens Shell Hedonic Hotspot Requires Endogenous Opioid Signals %A Kent C. Berridge %A Marci R. Mitchell %A Stephen V. Mahler %J Archive of "Cannabis and Cannabinoid Research". %D 2018 %R 10.1089/can.2018.0021 %X Introduction: Stimulating either endogenous cannabinoids or opioids within a restricted dorsomedial ˇ°hedonic hotspotˇ± in nucleus accumbens (NAc) shell enhances hedonic impact, or ˇ°likingˇ± reactions to sweet tastes. In this study, we probed within this hotspot the relationship between endocannabinoid and opioid signals in hedonic enhancement %K anandamide %K hedonic hotspot %K nucleus accumbens %K opioid %K pleasure %K taste reactivity %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069591/