%0 Journal Article
%T LncRNA MALAT1 promotes osteoarthritis by modulating miR-150-5p/AKT3 axis
%A Fuyou Wang
%A Guangxing Chen
%A Liu Yang
%A Rui He
%A Ying Zhang
%J Archive of "Cell & Bioscience".
%D 2019
%R 10.1186/s13578-019-0302-2
%X Different expression levels of MALAT1, miR-150-5p and AKT3 in normal and OA cartilage chondrocytes. a, b The expression levels of MALAT1, miR-150-5p and AKT3 in OA and normal cartilage tissues were detected by qRT-PCR and western blot. Samples were from 42 OA patients and 20 healthy subscribers. c Spearman was used to analyze the relationship between MALAT1, miR-150-5p and AKT3. d, e qRT-PCR and western blot were used to examine the levels of MALAT1, miR-150-5p and AKT3 in chondrocytes with treatment of 10 ng/mL IL-1¦Â for 4, 6, 12, and 24 h. *P£¿<£¿0.0
%K OA
%K MALAT1
%K miR-150-5p
%K AKT3
%K MALAT1/miR-150-5p/AKT3
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600894/