%0 Journal Article
%T Effects of Anti-Inflammatory Agents on Expression of Early Responsive
Inflammatory and Catabolic Genes in Ex Vivo Porcine Model of
Acute Knee Cartilage Injury
%A Amaris A. Genemaras
%A Brad Bradshaw
%A C.-Y. Charles Huang
%A Hayley Ennis
%A Lee Kaplan
%J Archive of "Cartilage".
%D 2018
%R 10.1177/1947603516684589
%X Early intervention therapies targeting inflammation and cell death during the acute phase of cartilage injury have the potential to prevent posttraumatic osteoarthritis. The objective of this study was to investigate the effects of interleukin receptor antagonist protein (IRAP), hyaluronan (HA), dexamethasone (DEX), and mesenchymal stem cell (MSC) treatment on the expression of established genetic markers for matrix degradation, apoptosis, and inflammation in articular cartilage during the acute phase of injury
%K early intervention
%K posttraumatic osteoarthritis
%K impact injury
%K microRNA
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042029/