%0 Journal Article
%T The Cannabinoids жд8THC, CBD, and HU-308 Act via Distinct Receptors to Reduce Corneal Pain and Inflammation
%A Anna-Maria Szczesniak
%A Dinesh Thapa
%A Elizabeth A. Cairns
%A James T. Toguri
%A Meggie D. Caldwell
%A Melanie E. M. Kelly
%J Archive of "Cannabis and Cannabinoid Research".
%D 2018
%R 10.1089/can.2017.0041
%X Background and Purpose: Corneal injury can result in dysfunction of corneal nociceptive signaling and corneal sensitization. Activation of the endocannabinoid system has been reported to be analgesic and anti-inflammatory. The purpose of this research was to investigate the antinociceptive and anti-inflammatory effects of cannabinoids with reported actions at cannabinoid 1 (CB1R) and cannabinoid 2 (CB2R) receptors and/or noncannabinoid receptors in an experimental model of corneal hyperalgesia
%K cannabinoids
%K cornea
%K pain
%K inflammation
%K hyperalgesia
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812319/