%0 Journal Article
%T Early Conversion from Tacrolimus to Belatacept in a Highly Sensitized Renal Allograft Recipient with Calcineurin Inhibitor-Induced de novo Post-Transplant Hemolytic Uremic Syndrome
%A Bonnie E. Lonze
%A Ming Wu
%A Robert A. Montgomery
%A Vasishta S. Tatapudi
%J Archive of "Case Reports in Nephrology and Dialysis".
%D 2018
%R 10.1159/000486158
%X Kidney transplantation is the first-line therapy for patients with end-stage renal disease since it offers greater long-term survival and improved quality of life when compared to dialysis. The advent of calcineurin inhibitor (CNI)-based maintenance immunosuppression has led to a clinically significant decline in the rate of acute rejection and better short-term graft survival rates. However, these gains have not translated into improvement in long-term graft survival. CNI-related nephrotoxicity and metabolic side effects are thought to be partly responsible for this
%K Tacrolimus
%K Belatacept
%K Hemolytic uremic syndrome
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836164/