%0 Journal Article
%T Two cases of primary leptomeningeal melanomatosis mimicking subacute meningitis
%A Asl£¿ Tuncer
%A Ekim Gumeler
%A Ethem Murat Arsava
%A Farid Khasiyev
%A Figen Soylemezoglu
%A Isin Unal Cevik
%A Mehmet Akif Top£¿uoglu
%A Nazire P£¿nar Acar
%A Rahsan Gocmen
%A Sabina Aslan
%J Archive of "The Neuroradiology Journal".
%D 2018
%R 10.1177/1971400917708581
%X Primary involvement of leptomeninges with melanocytic tumours is rarely seen and its diagnosis is challenging. Here we summarise two cases of primary leptomeningeal melanomatosis presenting as subacute meningitis. Both cases have pleocytosis and high protein on cerebrospinal fluid analysis, and demonstrated atypical cells on cytology. On magnetic resonance imaging, there is diffuse leptomeningal thickening and avid enhancement of intracranial and intraspinal leptomeninges. One of them demonstrates T1 shortening due to magnetic effects of melanin, the other case is amelanotic and shows hypointensity on precontrast T1-weighted images. Both cases can be diagnosed with biopsy. In conclusion, these cases highlight the importance of the correct interpretation of cytological and magnetic resonance imaging findings in patients with atypical findings
%K Magnetic resonance imaging
%K leptomeningeal melanocytosis
%K meningeal neoplasm
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789992/