%0 Journal Article
%T Two different STAT1 gain-of-function mutations lead to diverse IFN-¦Ã-mediated gene expression
%A Adi Ovadia
%A Chaim M. Roifman
%A Cynthia Hawkins
%A Nigel Sharfe
%A Suzanne Laughlin
%J Archive of "NPJ Genomic Medicine".
%D 2018
%R 10.1038/s41525-018-0063-6
%X CNS changes in the patient. Brain magnetic resonance imaging demonstrating white matter periventricular lesions, as shown in the a fluid-attenuated inversion recovery (FLAIR) image, and b T2-weighted image. c Haematoxylin & eosin/luxol fast blue staining of the brain biopsy shows (I) normal architecture with preservation of grey-white differentiation. Immunohistochemical staining with glial fibrillary acidic protein demonstrates white matter and subpial gliosis (II, III). Images were taken at varying magnification with scale bars as show
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102291/