%0 Journal Article
%T Shikimic Acid Promotes Oligodendrocyte Precursor Cell Differentiation and Accelerates Remyelination in Mice
%A Cheng He
%A Dou Yin
%A Fengfeng Lu
%A Li Cao
%A Qi Shao
%A Weili Liu
%A Yingyan Pu
%A Zhenghao Li
%J Archive of "Neuroscience Bulletin".
%D 2019
%R 10.1007/s12264-018-0322-7
%X SA increased myelin basic protein (MBP) expression in OPCs in vitro. A Structural formula of SA. B Western blots of MBP expression after 0.01 ¦Ìg/mL, 0.1 ¦Ìg/mL, 1 ¦Ìg/mL, 10 ¦Ìg/mL, and 100 ¦Ìg/mL SA treatment in cultured primary OPCs. C Representative images of immunofluorescence staining for MBP (red) in vehicle, SA (100 ¦Ìg/mL), and T3 groups. D Quantification of the relative expression levels of MBP protein as in B. E Numbers of MBP-positive cells as in C. Data are shown as mean£¿¡À£¿SEM. *P£¿<£¿0.05, **P£¿<£¿0.01, ***P£¿<£¿0.001, one-way ANOVA with Tukey¡¯s post hoc test. Scale bar, 50 ¦Ìm
%K Shikimic acid
%K Oligodendrocyte precursor cells
%K Demyelination
%K Remyelination
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527532/