%0 Journal Article
%T Medial septum activation produces opposite effects on dopamine neuron activity in the ventral tegmental area and substantia nigra in MAM vs. normal rats
%A Anthony A. Grace
%A David M. Bortz
%J Archive of "NPJ Schizophrenia".
%D 2018
%R 10.1038/s41537-018-0059-3
%X Representative placements, DA neuron identification, and drug infusion locations. a Population activity in the VTA was measured in nine sequential electrode tracks between AP £¿5.3 to 5.7 and ML 0.6¨C1.0. Arrows indicate three tracks across the medial¨Clateral span of the VTA. b Population activity is measured similarly in the SNc, between AP £¿4.9 to 5.3 and ML 2.0¨C2.4. Following the conclusion of the 9th track (top arrows), Chicago Sky Blue is ejected from the electrode leaving a blue dot for histological verification (bottom arrow). c Representative DA recording from the VTA and individual spike. The time bar for representative tracing equals 1£¿s, demonstrating a frequency of approximately six spikes per second. Arrows indicate three sets of spikes that are occurring in bursts. The time bar under the individual spike is 1.1£¿ms. Representative histology and matching illustration for the target region of the d MS and e vSub. The line in the illustration denotes the cannula placement and the arrow indicates the ventral termination of the cannula trac
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120917/