%0 Journal Article
%T Combining Human and Rodent Genetics to Identify New Analgesics
%A Alban Latremoliere
%A Michael Costigan
%J Archive of "Neuroscience Bulletin".
%D 2018
%R 10.1007/s12264-017-0152-z
%X Reverse-engineering a relevant pathway from pain patients into rodents and back to patients. A complex interplay needs to be established between the patient and the experimental animal in order to achieve rational therapy design most efficiently
%K Chronic pain
%K Genetics
%K Mouse models
%K Tetrahydrobiopterin
%K Sepiapterin reductase
%K Analgesics
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799129/