%0 Journal Article
%T Schizophrenia-related dysbindin-1 gene is required for innate immune response and homeostasis in the developing subventricular zone
%A Abeer R. Al-Shammari
%A Francis G. Szele
%A Ksenia Musaelyan
%A Lalit K. Srivastava
%A Sanjeev K. Bhardwaj
%J Archive of "NPJ Schizophrenia".
%D 2018
%R 10.1038/s41537-018-0057-5
%X Adult Sdy mice given postnatal polyI:C displayed schizophrenia relevant behavioural abnormalities. a Experimental design in which mice were injected at postnatal day 5 (P5) to P9, and characterized in adulthood. b Spontaneous locomotor activity at P70. c Mean startle amplitude (baseline level) to an acoustic pulse of 120 decibels in ten trials without any prepulses. d, e Percent of prepulse inhibition (PPI) to a main pulse of 120 decibels following prepulse (PP) intensities of 3, 6, 9, 12 or 15 decibels (5 trials per each PP). f Novel object recognition in adulthood. g Exploration times. All values are mean£¿¡À£¿s.e.m. of N£¿=£¿12¨C17 per group for (b) and N£¿=£¿12 per group for c¨Cg. Data were analyzed using two-way ANOVA for (c, g) with Tukey¡¯s post hoc test for (b, e) or Student¡¯s two-tailed t-test for (f). *P£¿<£¿0.05 and **P£¿<£¿0.0
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056426/