%0 Journal Article
%T Chemoprotective effect of nanocurcumin on 5-fluorouracil-induced-toxicity toward oral cancer treatment
%A Abbas Ali Mahdi
%A Fahad Mansoor Samadi
%A Rakesh Kumar Dixit
%A Saurabh Srivastava
%A Shadab Mohammad
%A Shalini Gupta
%A Vibha Singh
%J Archive of "National Journal of Maxillofacial Surgery".
%D 2018
%R 10.4103/njms.NJMS_27_18
%X Cancer of oral cavity is the uncontrolled expansion of damaged cell within the mouth cavity. 5-fluorouracil (5-FU) chemotherapy was focused to kill the cancer cell, but it would affect the surrounding normal cells during oral cancer treatment. This study included the evaluation of chemoprotective effects of curcumin (CU), as an herbal remedy, on 5-FU-induced-cytotoxicity toward oral cancer treatment, loaded within a nanocarrier system. CU was combined with 5-FU chemotherapy as a combinational drug-delivery system to evaluate synergistic effects
%K 5-fluorouracil
%K cellular-toxicity
%K curcumin
%K nanocarrier
%K oral cancer
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251302/