%0 Journal Article %T Use of Saline as a Placebo in Intra-articular Injections in Osteoarthritis: Potential Contributions to Nociceptive Pain Relief %A David Bar-Or %A Edward N. Brody %A Leonard T. Rael %J Archive of "The Open Rheumatology Journal". %D 2017 %R 10.2174/1874312901711010016 %X Osteoarthritis of the knee (OAK) is a severe debilitating condition characterized by joint pain, stiffness, and resultant limited mobility. In recent years, intra-articular (IA) injections have been used to relieve symptoms and have succeeded to varying degrees either with sodium hyaluronate preparations or with a biologic %K Biologicals %K Clinical trial %K Osteoarthritis %K Neuropathic pain %K Nociceptive pain %K Pain relief %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366377/