%0 Journal Article %T SLE and Serum Complement: Causative, Concomitant or Coincidental? %A Michele Quan %A Vaneet Sandhu %J Archive of "The Open Rheumatology Journal". %D 2017 %R 10.2174/1874312901711010113 %X Systemic Lupus Erythematosus (SLE) is an incurable autoimmune disorder with complement activation playing a key role in the pathogenesis of immune-mediated tissue injury. While quantifying complement to monitor SLE disease activity has been the standard of care since the 1950s, decreased complement levels are not consistently associated with flares %K SLE %K Systemic Lupus Erythematosus %K SLE flares' %K Complement %K CB-CAPS %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737025/