%0 Journal Article %T Anti-MDA5 Antibody Dermatomyositis Overlap with Systemic Lupus Erythematosus: A Case Report and Review of the Literature %A Andrew G. Franks Jr. %A Emily C. Milam %A Jacobo Futran %J Archive of "The Open Rheumatology Journal". %D 2016 %R 10.2174/1874312901610010122 %X Dermatomyositis (DM) is an autoimmune connective tissue disease that primarily targets the muscle, skin, and lungs. Many patients have autoantibodies that correspond to distinct clinical phenotypes. Melanoma differentiation-associated gene 5 (anti-MDA5) antibody, a specific antibody that targets the melanoma differentiation-associated gene 5 (MDA5), has been reported in DM cases and is significant for a distinct cutaneous presentation and rapidly progressive interstitial lung disease %K Connective tissue disease %K Dermatomyositis %K Melanoma differentiation-associated gene 5 (anti-MDA5) %K Systemic lupus erythematosus %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204063/