%0 Journal Article
%T Original research article: Increased levels of sST2 in patients with mitral annulus disjunction and ventricular arrhythmias
%A Andreea Motoc
%A Bernard Cosyns
%A Carlos Collet
%A Einar Hopp
%A Esther Scheirlynck
%A Eystein Skj£¿lsvik
%A Kaoru Tanaka
%A Kristina H Haugaa
%A Lars A Dejgaard
%A Margareth Ribe
%A Oyvind H Lie
%A Steven Droogmans
%A T Ueland
%A Thor Edvardsen
%J Archive of "Open Heart".
%D 2019
%R 10.1136/openhrt-2019-001016
%X Displacement of the mitral valve, mitral annulus disjunction (MAD), is described as a possible aetiology of sudden cardiac death. Stress-induced fibrosis in the mitral valve apparatus has been suggested as the underlying mechanism. We aimed to explore the association between stretch-related and fibrosis-related biomarkers and ventricular arrhythmias in MAD. We hypothesised that soluble suppression of tumourigenicity-2 (sST2) and transforming growth factor-¦Â1 (TGF¦Â1) are markers of ventricular arrhythmias in patients with MAD
%K mitral annulus disjunction
%K arrhythmia
%K biomarker
%K sST2
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519435/