%0 Journal Article
%T Viral RNA Degradation Makes Urine a Challenging Specimen for Detection of Japanese Encephalitis Virus in Patients With Suspected CNS Infection
%A Audrey Dubot-P¨Śr¨¨s
%A Christopher Gorman
%A G¨Śraldine Piorkowski
%A Jean-David Pommier
%A Jeremy A Garson
%A Malavanh Vongsouvath
%A Malee Seephonelee
%A Manivanh Vongsouvath
%A Marc Lecuit
%A Onanong Sengvilaipaseuth
%A Paul N Newton
%A Sayaphet Rattanavong
%A Tehmina Bharucha
%A Xavier de Lamballerie
%J Archive of "Open Forum Infectious Diseases".
%D 2019
%R 10.1093/ofid/ofz048
%X Japanese encephalitis virus (JEV) is a leading cause of central nervous system (CNS) infections in Asia and results in significant morbidity and mortality. JEV RNA is rarely detected in serum or cerebrospinal fluid (CSF), and diagnosis of JEV infection is usually based on serological tests that are frequently difficult to interpret. Unlike serum or CSF, urine is relatively easy to obtain, but, to date, there has been minimal work on the feasibility of testing urine for JEV RNA
%K diagnosis
%K flavivirus
%K Japanese encephalitis virus
%K RNA
%K RT-qPCR
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411208/