%0 Journal Article %T Direct-Acting Antiviral Treatment Failure Among Hepatitis C and HIV¨CCoinfected Patients in Clinical Care %A Alexander Wong %A Carmine Rossi %A Curtis Cooper %A Jim Young %A M John Gill %A Marina B Klein %A Sharon Walmsley %A The Canadian Co-Infection Cohort Investigators %A Val¨¦rie Martel-Laferri¨¨re %J Archive of "Open Forum Infectious Diseases". %D 2019 %R 10.1093/ofid/ofz055 %X There are limited data on the real-world effectiveness of direct-acting antiviral (DAA) treatment in patients coinfected with hepatitis C virus (HCV) and HIV¡ªa population with complex challenges including ongoing substance use, cirrhosis, and other comorbidities. We assessed how patient characteristics and the appropriateness of HCV regimen selection according to guidelines affect treatment outcomes in coinfected patients %K direct-acting antivirals %K hepatitis C virus %K HIV coinfection %K treatment failure %K treatment guidelines %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411211/