%0 Journal Article
%T Intravenous pathogenicity of influenza virus A/H5N1/2014 isolated from pig in Ogbomoso, Nigeria
%A E. Kolawole Oladipo
%A J. Adekunle Adeniji
%A J. Kola Oloke
%J Archive of "Open Veterinary Journal".
%D 2018
%R 10.4314/ovj.v8i3.16
%X Understanding the pathogenicity of avian influenza viruses in poultry is an important scientific and public health challenge because of antigenic shift/drift and a source of novel, potentially human-pathogenic strains. We have previously isolated an influenza A strain (H5N1/2014/Ogbomoso) from an outbreak among pig and have now aimed to assess its pathogenicity in an avian host and to categorize it as a low or high pathogenic strain. Intravenous pathogenicity index of the isolated virus was assayed using experimental infection of 6 weeks old pathogen-specific free chicken. The peak of clinical signs was on day three post-infection, and one death was observed on day eight. The intravenous pathogenicity index of this isolate was 0.08. This results classify this isolate as a low pathogenic avian influenza strain
%K H5N1
%K Influenza
%K Intravenous pathogenicity
%K Nigeria
%K Ogbomoso
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172407/