%0 Journal Article
%T When Ventricular Cerebrospinal Fluid Assessment Misleads: Basal Meningitis and the Importance of Lumbar Puncture Sampling
%A Alan C Street
%A Carly Hughes
%A Ian Jennens
%A Nicholas D P Hall
%A Ouli Xie
%A Sadid F Khan
%A Siddhartha Mahanty
%A Steven Y C Tong
%A Thornton Macauley
%J Archive of "Open Forum Infectious Diseases".
%D 2019
%R 10.1093/ofid/ofz324
%X The diagnosis of central nervous system (CNS) infection relies upon analysis of cerebrospinal fluid (CSF). We present 4 cases of CNS infections associated with basal meningitis and hydrocephalus with normal ventricular CSF but grossly abnormal lumbar CSF. We discuss CSF ventricular¨Clumbar composition gradients and putative pathophysiological mechanisms and highlight clinical clues for clinicians
%K cerebrospinal fluid
%K cryptococcal meningitis
%K lumbar puncture
%K meningitis
%K tuberculous meningitis
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667712/