%0 Journal Article %T Original research article: Biological variation of cardiac markers in patients with aortic valve stenosis %A Bas L J H Kietselaer %A Frederique E C M Peeters %A Harry J G M Crijns %A Judith Hilderink %A Marijke Niens %A Noreen van der Linden %A Steven J R Meex %J Archive of "Open Heart". %D 2019 %R 10.1136/openhrt-2019-001040 %X Cardiac biomarkers hold promise for follow-up and management of aortic valve stenosis (AVS). When interpreting serial biomarker measurements of patients with AVS, it can be challenging to distinguish ¡®real changes¡¯ from ¡®random fluctuation¡¯. Hence, robust estimation of the biological variation of these biomarkers is essential. In the present study we assessed biological variation of B-type natriuretic peptide (BNP), N-terminus pro-brain natriuretic peptide (NT-proBNP), high-sensitivity troponin-T and high-sensitivity troponin-I (hs-TnT and hs-TnI), and ST2 in subjects with stable AVS %K aortic valve stenosis %K progression %K cardiac biomarkers %K biological variation %K echocardiography %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519418/