%0 Journal Article %T Reactive oxygen species-dependent apoptosis induction by water extract of Citrus unshiu peel in MDA-MB-231 human breast carcinoma cells %A Cheol Park %A Da He Kwon %A Eun Ok Choi %A Gi Young Kim %A Hong Jae Kim %A Hyun HwangBo %A Jin-Woo Jeong %A Kyu Im Ahn %A Min Yeong Kim %A Seon Yeong Ji %A Su-Hyun Hong %A Yung Hyun Choi %J Archive of "Nutrition Research and Practice". %D 2018 %R 10.4162/nrp.2018.12.2.129 %X Although several recent studies have reported the anti-cancer effects of extracts or components of Citrus unshiu peel, which has been used for various purposes in traditional medicine, the molecular mechanisms for their effects remain unclear. In the present study, the anti-cancer activity of a water-soluble extract of C. unshiu peel (WECU) in MDA-MB-231 human breast carcinoma cells at the level of apoptosis induction was investigated %K Citrus unshiu %K apoptosis %K caspase %K cytotoxicity %K ROS %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886964/