%0 Journal Article
%T Cytotoxic, DNA Cleavage and Pharmacokinetic Parameter Study of Substituted Novel Furan C-2 Quinoline Coupled 1, 2, 4-Triazole and Its Analogs
%A Bhuvanesh Sukhlal Kalal
%A Nayak D. Satyanarayan
%A Rajpurohit Anantacharya
%A Vinitha Ramanath Pai
%J Archive of "The Open Medicinal Chemistry Journal".
%D 2018
%R 10.2174/1874104501812010060
%X Furan, quinoline and triazoles are known for their wide spectrum biologically active molecules. A series of novel furan C-2 quinoline and 1, 2, 4-triazole (FQT) coupled hybrids were designed and synthesized to evaluate for their DNA cleavage and cytotoxic studies
%K Cancer
%K Melanoma cell line
%K Breast cancer cell line
%K ADMET
%K Cytotoxic
%K Quinoline
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997846/