%0 Journal Article
%T Functional Exploration Of T-Type Calcium Channels (Cav3.2 And Cav3.3) And Their Sensitivity To Zinc
%A Fechtali Taoufiq
%A Tahar Hazzaz Abouamal
%A Zineb Choukairi
%J Archive of "The Open Microbiology Journal".
%D 2018
%R 10.2174/1874285801812010280
%X T-type Ca2+ channels (TTCC) are low Voltage-gated calcium channels, expressed in various tissues such as the brain and heart, and contribute to a variety of physiological functions including neuronal excitability, hormone secretion, muscle contraction, and pacemaker activity. At high concentrations, Zinc (Zn2+) is naturally attached to cell membranes and is therefore considered a reversible inhibitor of calcium. Zinc is also involved in the kinetics of sodium and potassium currents. Zinc is essential for many functions. A low zinc tenor is associated with emotional instability, digestive disorders, slow-growing and alteration of protein synthesis
%K Voltage gated channel
%K t-type calcium channel
%K Electrophysiology
%K Patch Clamp
%K Perferential Blocker
%K Electrophysiological
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110071/