%0 Journal Article
%T The CD39-Adenosinergic Axis in the Pathogenesis of Immune and Nonimmune Diabetes
%A Joanne S. J. Chia
%A Jennifer L. McRae
%A Peter J. Cowan
%A Karen M. Dwyer
%J Journal of Biomedicine and Biotechnology
%D 2012
%I Hindawi Publishing Corporation
%R 10.1155/2012/320495
%X Diabetes mellitus encompasses two distinct disease processes: autoimmune Type 1 (T1D) and nonimmune Type 2 (T2D) diabetes. Despite the disparate aetiologies, the disease phenotype of hyperglycemia and the associated complications are similar. In this paper, we discuss the role of the CD39-adenosinergic axis in the pathogenesis of both T1D and T2D, with particular emphasis on the role of CD39 and CD73.
%U http://www.hindawi.com/journals/biomed/2012/320495/