%0 Journal Article %T Preliminary evidence that hydroxyurea is associated with attenuated peripheral sensitization in adults with sickle cell disease %A Christopher Patrick Carroll %A Claudia M. Campbell %A Janelle E. Letzen %A Jennifer A. Haythornthwaite %A Kasey Bond %A Sabrina Nance %A Sophie Lanzkron %J Archive of "Pain Reports". %D 2019 %R 10.1097/PR9.0000000000000724 %X Hydroxyurea (HU) is a drug that targets the underlying pathophysiology of sickle cell disease (SCD); however, it continues to be an underutilized treatment for adults. Previous research suggests that HU treatment can result in fewer hospital contacts for acute vaso-occlusive pain crises (VOC). Hydroxyurea's impact on non-VOC pain, however, is not well established %K Sickle cell disease %K Hydroxyurea %K Quantitative sensory testing %K VOC pain %K Chronic pain %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455681/