%0 Journal Article
%T Epiregulin is released from intervertebral disks and induces spontaneous activity in pain pathways
%A Daniel Pitz Jacobsen
%A Fred Haugen
%A Johannes Gjerstad
%A Mette Kongstorp
%A Tiril Schj£¿lberg
%J Archive of "Pain Reports".
%D 2019
%R 10.1097/PR9.0000000000000718
%X Lumbar radicular pain after disk herniation is associated with local release of many inflammatory molecules from nucleus pulposus (NP) cells leaking out of the intervertebral disk. Here, we have used a rat model to investigate the role of epiregulin (EREG), a member of the epidermal growth factor (EGF) family, in this process
%K Disk herniation
%K Inflammation
%K Growth factors
%K Epiregulin
%K EREG
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455685/