%0 Journal Article
%T HPV16 variant analysis in primary and recurrent CIN2/3 lesions demonstrates presence of the same consensus variant
%A Audrey J. King
%A Chris J.L.M. Meijer
%A Pascal van der Weele
%A Renske D.M. Steenbergen
%J Archive of "Papillomavirus Research".
%D 2019
%R 10.1016/j.pvr.2019.04.008
%X Recurrent cervical intraepithelial lesions (rCIN2/3) after treatment of CIN2/3 occur in 5¨C15% of cases. rCIN2/3 can result from incomplete resection of CIN2/3, where the same HPV type and variant remains present. rCIN2/3 could also occur following a new infection with a different HPV variant of the same HPV type as the initial lesion. This study investigates HPV16 consensus variants in paired HPV16 positive scrapes from baseline CIN2/3 and rCIN2/3 lesions
%K Whole-genome sequencing
%K HPV16
%K HPV genome variants
%K CIN
%K rCIN
%K Recurrent infection
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477513/