%0 Journal Article
%T Parotid Sinus Secondary to Granulomatosis with Polyangiitis: A Case Report
%A Mohamed Elqersh
%A Mohamed Zahran
%J Archive of "OTO Open".
%D 2019
%R 10.1177/2473974X18818416
%X Granulomatosis with polyangiitis (GPA) or WegenerĄ¯s granulomatosis is a multisystemic disease with a complex genetic background. The clinical presentations are characterized by necrotizing granulomatous inflammation of the upper and lower respiratory tract, glomerulonephritis, and small-vessel vasculitis.1 Systemic symptoms of GPA are nonspecific and include fatigue, fever, arthralgia, and weight loss. Head and neck manifestations occur in 90% of patients. The nose and paranasal sinuses are most commonly affected in up to 80%.2 Nasal symptoms include serosanguinous discharge and headache and pain over the dorsum. Nasal findings include crusts covering friable mucosa, ulceration, septal perforation, and saddle-nose deformity. Involvement of salivary glands occurs in less than 1%.3 A high level of clinical suspicion and appropriate diagnostic and laboratory investigations are crucial for early diagnosis. We report a case of bilateral parotid gland swelling and pus-draining parotid sinus secondary to GPA and discuss its presentations and management. The study was approved by the ethics committee of Alexandria Faculty of Medicine
%K WegnerĄ¯s granulomatosis
%K granulomatosis with polyangiitis
%K parotid sinus
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572921/