%0 Journal Article %T Magnetic resonance imaging in the diagnosis of white matter signal abnormalities %A Asuri Narayan Prasad %A Charles Anthony Rupar %A Chitra Prasad %A Keng Yeow Tay %A Michael Miller %A Pavlo Ohorodnyk %A Ravi Datar %J Archive of "The Neuroradiology Journal". %D 2018 %R 10.1177/1971400918764016 %X White matter abnormalities (WMAs) pose a diagnostic challenge when trying to establish etiologic diagnoses. During childhood and adult years, genetic disorders, metabolic disorders and acquired conditions are included in differential diagnoses. To assist clinicians and radiologists, a structured algorithm using cranial magnetic resonance imaging (MRI) has been recommended to aid in establishing working diagnoses that facilitate appropriate biochemical and genetic investigations. This retrospective pilot study investigated the validity and diagnostic utility of this algorithm when applied to white matter signal abnormalities (WMSAs) reported on imaging studies of patients seen in our clinics %K White matter abnormalities %K myelination %K magnetic resonance imaging %K diagnostic utility %K diagnostic neuroradiology %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111436/